About us

The Moon (Sleep) Lab for Artificial Intelligence Technology (MoonLAIT), led by Yue Leng, PhD, is not just another research lab; it is where data, sleep science, and innovation come together to redefine our understanding of neurodegenerative diseases like Alzheimer’s and Parkinson’s. We explore the untapped frontiers of sleep research, employing big data and machine learning, and aim to be trailblazers in early detection and intervention strategies for neurodegenerative diseases.

Check out our ongoing research projects!

Happening now at MoonLAIT

We are hiring! 

We are looking for highly motivated individuals to join our team. We are considering applications for posztdoctoral scholars, data analysts, and research coordinators. Click here to learn how to apply!

New R01 grant 

We are excited to announce that Dr. Leng has received a new NIH R01 award for the LifeSPAN project focused on lifecourse sleep, cognitive decline and risk of Alzheimer's disease. Click here to learn more about the project.

Recent publications 

2025:

Racial and Ethnic and Sex Differences in At-Home Estimates of Obstructive Sleep Apnea Parameters among Diverse Adults

Annals of the American Thoracic Society (2025)

Leng Y, Cavaillès C, Peltz C, O'Bryant S, Redline S, Yaffe K.

 

Five-Year Changes in 24-Hour Sleep-Wake Activity and Dementia Risk in Oldest Old Women

Neurology (2025)

Milton S, Cavaillès C, Ancoli-Israel S, Stone K, Yaffe K, Leng Y.

 

Association of rapid eye movement sleep latency with multimodal biomarkers of Alzheimer's disease

Alzheimer's & Dementia​ (2025)

Jin J, Chen J, Cavaillès C, Yaffe K, Winer J, Stankeviciute L, Lucey BP, Zhou X, Gao S, Peng D, Leng Y.

2024:

Snoring and risk of dementia: a prospective cohort and Mendelian randomization study

Sleep (2024)

Gao Y, Andrews S, Daghlas I, Brenowitz W, Raji C, Yaffe K, Leng Y.

 

Harnessing Brain Pathology for Dementia Prevention

JAMA Neurology (2024)

Leng Y & Yaffe K.

 

Association Between Sleep Quantity and Quality in Early Adulthood With Cognitive Function in Midlife

Neurology (2024)

Leng Y, Knutson K, Carnethon MR, Yaffe K.

2023:

Multidimensional Sleep Health and Long-Term Cognitive Decline in Community-Dwelling Older Men

Journal of Alzheimer's Disease (2023)

Cavaillès C, Yaffe K, Blackwell T, Buysse D, Stone K, Leng Y.